Some people do not tolerate gluten very well, if at all.
The problem is that many of the most consumed grains contain gluten. However, there are also plenty of nutritious gluten-free grains available.
Further reading: https://www.healthline.com/nutrition/9-gluten-free-grains
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STUDY 1: https://www.ncbi.nlm.nih.gov/pubmed/15184005
STUDY 2: https://www.ncbi.nlm.nih.gov/pubmed/20673059
STUDY 3: https://www.ncbi.nlm.nih.gov/pubmed/24608948
STUDY 4: https://www.ncbi.nlm.nih.gov/pubmed/25411276
STUDY 5: https://www.ncbi.nlm.nih.gov/pubmed/24431078
STUDY 6: https://www.ncbi.nlm.nih.gov/pubmed/21419317
STUDY 7: https://www.ncbi.nlm.nih.gov/pubmed/24829736